A randomised controlled trial of bismuth in the treatment of functional diarrhoea

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN86357226

Enrollment

Registered

2003-09-12

Start date

1999-09-13

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System: Diarrhoea Digestive System Diarrhoea

Interventions

1. Bismuth treatment group 2. Placebo Added July 2008: trial never started, due to poor recruitment and lack of resources.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age range of subjects: patients = 18-80 years; control patients 18-80 years 2. Sex of subjects: patients = both; control patients = both

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Symptom Score (Bowel frequency/day, days of pain/week, presence of urgency, stool consistency), enteroendocrine cell and intraepithelial lymphocyte count on rectal biopsy.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026