The EPICure2 Study: educational and health outcomes at 11 years of age following extremely preterm birth

The EPICure Studies: Outcome at 11 years for a national cohort of births between 22 and 26 weeks of gestation in England in 2006

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN86323684

Enrollment

1040

Registered

2016-11-30

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Birth between 22 and 26 weeks of gestation Pregnancy and Childbirth Prematurity

Interventions

Children will be assessed in their school environment using a range of neuropsychological and education tests, and cardiorespiratory assessments over one school day. Information will also be sought by

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Birth during 2006 2. Born at 22-26 weeks of gestation 3. Mother resident in England

Exclusion criteria

Exclusion criteria: 1. Having moved outside the UK 2. Family has withdrawn from the study

Design outcomes

Primary

Measure	Time frame
IQ is measured using The Kaufmann-ABC (second edition) at 11 years of age.	—

Secondary

Measure	Time frame
1. Educational attainment is measured using teacher questionnaire, direct assessment (WIAT-II UK) and the results of national attainment tests at Key Stage 2 2. Behavioural outcomes will be measured using the Strengths and Difficulties Questionnaire, supplemented with the du Paul RS-IV scale for attentional problems and the Social Communication Questionnaire, which will be combined with the results of a post assessment parental interview using the Development and Wellbeing Assessment 3. Lung function measured using spirometry, exercise capacity (incremental walk test and 24h activity monitoring and clinical history 4. Blood pressure and augmentation index are measured using conventional blood pressure measurements and Doppler circulation assessment respectively	—

Measure

Time frame

1. Educational attainment is measured using teacher questionnaire, direct assessment (WIAT-II UK) and the results of national attainment tests at Key Stage 2 2. Behavioural outcomes will be measured using the Strengths and Difficulties Questionnaire, supplemented with the du Paul RS-IV scale for attentional problems and the Social Communication Questionnaire, which will be combined with the results of a post assessment parental interview using the Development and Wellbeing Assessment 3. Lung function measured using spirometry, exercise capacity (incremental walk test and 24h activity monitoring and clinical history 4. Blood pressure and augmentation index are measured using conventional blood pressure measurements and Doppler circulation assessment respectively

—

Countries

England, United Kingdom

Contacts

Public ContactLaura McCormack

epicure@ucl.ac.uk+44 20 3108 2045

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 14, 2026