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Feasibility study for a randomised controlled trial evaluating the use of absorbable mesh, polydioxanone and polyglactin sutures for anterior and posterior vaginal wall prolapse repairs

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN86144697
Enrollment
70
Registered
2005-09-15
Start date
2005-05-15
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolapse Urological and Genital Diseases Female genital prolapse

Interventions

A randomised controlled trial using a 2x2 factorial design of absorbable mesh compared with no mesh, and two types of sutures for anterior or posterior pelvic organ prolapse repair.

Sponsors

University of Aberdeen (UK)
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All women admitted for primary pelvic organ prolapse surgery with grade 2 or more pelvic organ prolapse who are willing to participate in the trial. Women undergoing concurrent hysterectomy or continence procedures will also be eligible.

Exclusion criteria

Exclusion criteria: Women with less than a grade 2 prolapse, those unwilling or unable to participate in the trial.

Design outcomes

Primary

MeasureTime frame
Recurrence of (or failure to cure) prolapse symptoms. One of the aims of the feasibility study is to test how best to assess these outcome measures and their inclusiveness.

Secondary

MeasureTime frame
1. Immediate and late postoperative morbidity 2. Recurrence of prolapse 3. Quality of life 4. Satisfaction with surgery and economic outcomes

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026