Ischemic stroke (first event) Circulatory System Ischemic stroke, cerebral infarction
Conditions
Interventions
Patients with incident first stroke who live in their own homes will be included in this cohort study. At 3, 6, 9, and 12 months after stroke a battery of mobility tests will be performed at the study
Sponsors
University of Basel
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. First ischemic stroke within the past 3 months 2. Aged =18 years 3. Able to communicate verbally with the study personnel 4. Able to understand the study information and to provide written informed consent 5. At least one of the following stroke-related symptoms potentially affecting gait/mobility must be present: 5.1. Lower limb paresis or ataxia 5.2. Stance/gait ataxia (cerebellar or sensory) 5.3. Visual disturbance/field defect 5.4. Central vestibular deficit 5.5. Attentional deficit/neglect 6. Able to get up from a chair and sit down without external help 7. Able to walk for a minimum of 20 m at own pace, with or without pauses, with or without a walking aid, but without the physical assistance of another person (self-report)
Exclusion criteria
Exclusion criteria: 1. Not community-dwelling 2. Unable to walk without assistance, wheelchair-bound, or permanently bedridden (modified Rankin Scale, mRS >3 points) 3. Presence of severe cognitive impairment (Montreal Cognitive Assessment (MoCA) score <21 or, <20 for persons with 12 years of education or less) 4. Acute psychiatric disorder (e.g. severe depression) 5. Advanced terminal illness 6. Orthopaedic surgery of the lower extremities within the past year 7. On-going rehabilitation measures following an inpatient surgical procedure at the time of stroke 8. Major pre-stroke mobility limitations (major difficulties in walking or climbing stairs; self-report)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Walking ability and perceived mobility limitation assessed by self-report at 3, 6, 9, and 12 months after stroke 2. Lower extremity physical function measured using a battery of tests including quantitative gait analysis, tests of lower limb muscle power, balance tests and functional tests in a given order at the study centre assessed at 3, 6, 9, and 12 months after stroke 3. Life-space measured using GPS and by self-report questionnaire at 3, 6, 9, and 12 months after stroke 4. Reasons for going outdoors, transportation use, and need for assistance measured using a questionnaire tool that is based on digital maps at 3, 6, 9, and 12 months after stroke | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
Switzerland
Outcome results
None listed