Gastrointestinal haemorrhage Digestive System
Conditions
Interventions
Patients who have been referred for conventional upper and lower GI investigation to investigate their iron deficiency anemia will be invited to undergo a magnetically assisted capsule endoscopy proce
Sponsors
Sheffield Teaching Hospital NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years and over and up to but not exceeding 80 years 2. Patients presenting with IDA whom require gastroscopy and colonoscopy is indicated as per national guidelines
Exclusion criteria
Exclusion criteria: 1. Patients under the age of 18 years 2. Patients over the age of 80 years 3. Active vomiting 4. Patients with a permanent pacemaker, implantable cardioverter-defibrillator or REVEAL device 5. Patients with any electronic/magnetic/mechanically controlled devices e.g. sacral nerve stimulators, bladder stimulators 6. Patients with dysphagia, odynophagia or known swallowing disorder 7. Patients with known Zenker’s diverticulum 8. Patients with suspected bowel obstruction or bowel perforation 9. Patients with prior bowel obstruction 10. Patients with gastroparesis or known gastric outlet obstruction 11. Patients with known Crohn’s disease 12. Patients who are taking daily non-steroidal anti-inflammatory drugs (excluding prophylactic doses of aspirin) for more than six months 13. Patients who have received abdominopelvic radiotherapy treatment 14. Patients with a history of GI tract surgery (Billroth I, Billroth II, Oesophagectomy, gastrectomy or bariatric procedure) 15. Patients that are pregnant or lactating 16. Patients with altered mental status that would limit their ability to swallow 17. Patients with allergy to conscious sedation or metoclopramide 18. Patients unwilling to swallow the capsule 19. Patients with known dementia affecting ability to consent 20. Patients who are unable to understand or speak English 21. Patients unable to provide written informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prevalence and nature of lesions in the upper GI tract, small bowel and colon that cause Iron deficiency anaemia, measured using magnetically assisted capsule endoscopy; Timepoint(s): end of study assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The diagnostic yield of the upper GI magnetic controlled capsule endoscopy compared with conventional gastroscopy following both procedures 2. Patient-reported tolerance of capsule endoscopy and gastroscopy measured using a questionnaire following both procedures | — |
Countries
England, United Kingdom
Outcome results
None listed