Cardiovascular diseases: Peripheral arterial disease Circulatory System Peripheral arterial disease
Conditions
Interventions
1. Autologous transfusion: acute normovolaemic haemodilution and intragerative cell salvage
2. Homologous transfusion: homologous blood if required
Sponsors
NHS R&D Regional Programme Register - Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients undergoing elective surgery for either occlusive or aneurysmal arterial disease will be asked to give written informed consent: 1. Both men and women aged 30-85 2. Considered fit for aortic surgery without any of the exclusion criteria 3. Pre-operative haemoglobin >11 g/dl and platelet count >150 x 10^9/1 4. Adequate cardiac and pulmonary function clinically
Exclusion criteria
Exclusion criteria: Any patient unfit for aortic surgery, unable for any reason to receive either autologous or standard transfusion therapy, or undergoing emergency surgery for suspected rupture of an aneurysm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood transfusion requirements, haematological and haemostatic parameter, post-operative infection, morbidity and hospital stay, economic analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed