To compare the safety and efficacy of 'low dose' vaginal misoprostol and dinoprostone vaginal gel for induction of labour at term

A single-blind randomised controlled trial comparing low dose vaginal misoprostol and dinoprostone vaginal gel for inducing labour at term

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN85744560

Enrollment

200

Registered

2003-09-12

Start date

2000-07-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth: Induction of labour Pregnancy and Childbirth

Interventions

1. Misoprostol 2. Dinoprostone

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women at term (37-42 completed weeks of pregnancy) 2. Single fetus, cephalic presentation 3. Membranes may be intact or ruptured 4. Reactive fetal heart tracing

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Secondary

Measure	Time frame
Not provided at time of registration	—

Primary

Measure	Time frame
1. Uterine tachysystole 2. Hyperstimulation 3. Presence of meconium in the amniotic fluid 4. Apgar Scores at 5 min. Umbilical arterial pH and base deficit 5. Neonatal Unit admission 6. Induction - delivery interval 7. Method of delivery 8. Bishop score at onset of labour 9. Oxytocin requirements in labour 10. Mode of delivery 11. Analgesia requirements in labour	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026