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Estimating uptake of colorectal cancer screening tests

Which colorectal cancer screening test would achieve the highest level of uptake? A survey of public attitudes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN85697880
Enrollment
3040
Registered
2013-04-25
Start date
2013-05-13
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Primary Care Research Network for England / Colorectal cancer screening Cancer Malignant neoplasm of colon and rectum

Interventions

Eligible individuals will be randomised to receive information and a questionnaire regarding one of four bowel cancer screening tests: 1. Flexible-sigmoidoscopy: An internal camera exam that examines
patients would be required to administer an enema before the test 2. Colonoscopy: Another internal camera exam but one that examines the full length of the large bowel
theoretically, it can find and prevent more cancers but also has more risks than flexible sigmoidoscopy
patients would have to undergo a powerful laxative before the test 3. Non-laxative CT colonography: A scan exam that can find and prevent almost as many cancers as colonoscopy with fewer risks and wit

Sponsors

UCL/UCLH/Royal Free Biomedical Research Unit (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Male and female aged 45-54 years 2. Clinically judged to be suitable to receive a questionnaire and information on a bowel cancer screening test (see exclusion criteria below)

Exclusion criteria

Exclusion criteria: 1. Previous diagnosis of bowel cancer or recent diagnosis of other cancer 2. Terminal illness 3. Learning disability 4. Receives regular colonoscopies 5. Experiencing significant cognitive decline

Design outcomes

Primary

MeasureTime frame
Intention to be screened; Timepoint(s): When questionnaire is returned by post to the main study office

Secondary

MeasureTime frame
Current secondary outcome measures as of 08/05/2013: 1. Perceived accuracy; Timepoint(s): When questionnaire is returned by post to the main study office 2. Perceived benefits; Timepoint(s): When questionnaire is returned by post to the main study office 3. Perceived preparation burden; Timepoint(s): When questionnaire is returned by post to the main study office 4. Perceived test burden; Timepoint(s): When questionnaire is returned by post to the main study office 5. Preferred surveillance modality; Timepoint(s): When questionnaire is returned by post to the main study office Previous secondary outcome measures until 08/05/2013: 1. Perceived accuracy; Timepoint(s): When questionnaire is returned by post to the main study office 2. Perceived benefits; Timepoint(s): When questionnaire is returned by post to the main study office 3. Perceived preparation burden; Timepoint(s): When questionnaire is returned by post to the main study office 4. Perceived test burden; Timepoint(s): When questionnaire is returned by post to the main study office

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 12, 2026