COVID-19 (SARS-CoV-2 infection) Infections and Infestations
Conditions
Interventions
An exploratory study investigating the trajectory of vital signs in hospitalised level one patients with COVID-19. This is a single-site hospital-based study using data collected as part of the usual
Sponsors
University of Oxford
Eligibility
Sex/Gender
All
Age
18 Years to 110 Years
Inclusion criteria
Inclusion criteria: 1. Male or female, aged 18 years or above 2. Diagnosed with COVID-19 3. Admitted to a ward using the Virtual HDU monitoring system
Exclusion criteria
Exclusion criteria: Not monitored using the Virtual HDU system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The physiological pattern of vital signs over the course of COVID-19 infection for hospitalised level 1 patients that used the vHDU system (ambulatory monitoring of vital signs), determined by measuring the frequency and duration of periods for which at least one vital sign (pulse rate, respiratory rate, blood oxygen saturation, blood pressure, Glasgow Coma Scale score and temperature) exceeds local Track and Trigger (Early Warning Score) thresholds, throughout the duration of each patient’s monitored hospital admission. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The frequency and timing of deteriorations occurring during the monitored hospital admission for each patient (defined as periods for which at least one vital sign (pulse rate, respiratory rate, peripheral oxygen saturation, blood pressure, Glasgow Coma Scale score and temperature) exceeds local Track and Trigger thresholds) detected using continuous vital signs monitoring compared with those detected using intermittent vital signs measurements. 2. Number of adverse events in COVID-19 patients monitored via the ambulatory monitoring system: the number of in-hospital deaths, admissions to intensive care, escalation of care to NIV/HFNO and cardiac arrest calls documented in the care record as occurring during the monitored hospital admission for all patients 3. The number of deterioration events during the monitored hospitalisation period preceding an adverse event for those patients who experience an adverse event compared with the number of deterioration events in patients who did not experience an adverse event during their monitored hospital admission. 4. Escalation thresholds for both local Early Warning Scores and National Early Warning Score 2 will be applied to continuous vitals data throughout the monitored hospitalised period for each patient. Duration and frequency of continuous vital signs data meeting escalation thresholds will be compared between the two scoring systems. 5. Heart rate, respiratory rate and peripheral oxygen saturation measurements entered into the local electronic track and trigger system during each patient’s monitored hospital admission will be compared with data recorded by the ambulatory monitoring system for the same parameter at the closest timepoint. 6. AMS system reliability measured using the number of hours of continuous vital-sign data acquired by the pulse oximeter and the chest patch during the time each patient was registered on the ambulatory monitoring system | — |
Countries
England, United Kingdom
Outcome results
None listed