T1N0M0 papillary thyroid carcinoma Cancer
Conditions
Interventions
A propensity score matching was used to evaluate the outcomes of radiofrequency ablation or microwave ablation for the treatment of T1N0M0 papillary thyroid carcinoma.
RFA or MWA was
Sponsors
First Affiliated Hospital of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Solitary papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration 2. Tumors with a maximum diameter =20 mm 3. No clinical or imaging evidence of extrathyroidal extension, lymph node metastases and distant metastases on ultrasound, and neck and chest CT 4. No history of neck irradiation 5. Follow-up period =24 months
Exclusion criteria
Exclusion criteria: 1. Convincing evidence of aggressive type on biopsy 2. Multiple tumors 3. Incomplete data or lost to follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease progression, defined as follows: 1. Cervical lymph node metastases confirmed by biopsy 2. Recurrent tumor confirmed by biopsy 3. Persistent tumor (residual tumor at the site of the ablated tumor) confirmed malignant by biopsy 4. Distant metastases confirmed by chest CT Recurrence-free survival was calculated from treatment initiation to disease progression or the last follow-up visit | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Volume reduction = ([initial volume-final volume] × 100)/initial volume measured using ultrasound at 1, 3, 6, 12 months, and every 6-12 months thereafter 2. Tumor complete disappearance (complete disappearance of the ablated tumor on ultrasound and contrast-enhanced ultrasound) at 1, 3, 6, 12 months, and every 6-12 months thereafter 3. Complications, recorded by the standard for image-guided thyroid ablation after RFA or MWA treatment | — |
Countries
China
Contacts
Public ContactYukun Luo
Outcome results
None listed