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Pretreatment with vaginal misoprostol before vacuum aspiration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN85366519
Enrollment
4464
Registered
2004-04-01
Start date
2001-12-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Induced abortion Pregnancy and Childbirth Abortion

Interventions

Misoprostol (0.4 mg) versus placebo tablet three hours before vacuum aspiration. Approximate duration of involvement in the study for each subject is one follow up visit ten days post-treatment.

Sponsors

UNDP/UNFPA/WHO/World Bank - Special Programme of Research, Development and Research Training in Human Reproduction
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Pregnancy of less than 12 completed weeks 2. Be informed about the study and sign a consent form 3. Agree to return for a follow-up visit five to ten days after surgery

Exclusion criteria

Exclusion criteria: No exclusion criteria

Design outcomes

Primary

MeasureTime frame
Will evaluate if preoperative treatment with 0.4 mg misoprostol administered vaginally three hours before vacuum aspiration can reduce complications of surgical first trimester abortion.

Secondary

MeasureTime frame
No secondary outcome measures

Countries

Armenia, China, Cuba, Hungary, India, Mongolia, Romania, Slovenia, Viet Nam

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 26, 2026