Stroke rehabilitation Circulatory System Stroke, not specified as haemorrhage or infarction
Conditions
Interventions
In the intervention group, patients will receive a 30-minute session of EEG-NF training, 5 days a week for a total duration of 6 weeks (30 sessions). The EEG will be recorded from three sensors placed
Sponsors
East Kent Hospitals University NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Two to 12 weeks from stroke onset 2. First ever stroke 3. Right hemisphere cortical involvement, confirmed on neuroimaging 4. Significant visual neglect, defined as a behavioural inattention test (BIT) score of 129 or less (maximum possible 146) 5. No other significant cognitive or communication problem 6. Informed consent for participation and follow-up 7. Both sexes, aged 18 - 85 years
Exclusion criteria
Exclusion criteria: 1. Unable to provide consent 2. Unable to comply with training or assessment procedures for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Behavioural Inattention Test (BIT) measured at 6 weeks after randomisation. BIT will also be measured 12 weeks after randomisation (6 weeks after completion of EEG-NF training) to assess sustainability. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Attentional Network Test (ANT), measured 6 and 12 weeks after randomisation 2. Barthel Index (BI), measured 6 and 12 weeks after randomisation 3. Nottingham Extended Activities of Daily living (NEADL) for activity and participation, measured 6 and 12 weeks after randomisation 4. Hospital Anxiety and Depression Scale (HADS) for mood, measured 6 and 12 weeks after randomisation 5. Five dimensional EuroQol (EQ-5D) and the visual analogue scale (EQ-VAS) for quality of life, measured 6 and 12 weeks after randomisation 6. Quantitative-EEG (Q-EEG) and functional magnetic resonance imaging, measured at baseline and 6 weeks in 36 patients to investigate underlying cortical changes with recovery and intervention 7. The number of patients consenting to EEG-NF training, number completing the programme, sessions completed and ability to modulate various EEG frequencies will be documented to assess acceptability 8. Ease of use including staff training requirements and the feasibility of integrating with existing therapy programmes 9. The semi-structured interview will be analysed for patient views on benefits of treatment, acceptability of training and perceived benefits of the training programme | — |
Countries
United Kingdom
Outcome results
None listed