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Efficacy of magnesium and sotalol in prevention of Atrial fibrillation (AF) following cardiac surgery

Efficacy of magnesium and sotalol in prevention of Atrial fibrillation (AF) following cardiac surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN85229111
Enrollment
200
Registered
2004-09-30
Start date
2003-12-01
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular: Atrial fibrillation (AF) Circulatory System Atrial fibrillation (AF)

Interventions

2 groups - a control group given placebo and a study group given sotalol with magnesium. Preoperative assessment of electrocardiogram (ECG), serum potassium and magnesium levels. ECG

Sponsors

Department of Health
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Therapeutic research: All patients admitted for cardiac surgery in The Cardiothoracic centre are potential participants. All the details of the study are explained to the patients and a patient information sheet is given to them. Following this, a proper consent is obtained.

Exclusion criteria

Exclusion criteria: 1. Patients who are in another trial that might have a bearing or influence in outcome in this study 2. Patients undergoing aortic procedure, preoperative atrial fibrillation or second or third degree heart block and patients with preoperative creatinine value of more than 200.

Design outcomes

Primary

MeasureTime frame
1. To monitor the frequency of atrial fibrillation following pre-operative treatment with sotalol and magnesium and to determine its efficacy in a large group of cardiac surgery patients. 2. The prevention of Atrial Fibrillation in patients undergoing Cardiac Surgery

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026