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The use of ultrasound imaging to estimate fluid status to guide the treatment of patients hospitalised with heart failure

Lung ultrasound-guided diuretic therapy in patients hospitalized with acute decompensated heart failure: an open-label interventional clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN85160756
Enrollment
300
Registered
2021-08-31
Start date
2021-12-19
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute decompensated heart failure Circulatory System Heart failure, unspecified

Interventions

Eligible participants who are hospitalized with ADHF in general medical wards or high dependency unit at Sultan Qaboos University Hospital (SQUH) will be invited to participate in the study after sign

Sponsors

Sultan Qaboos University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patient admitted with ADHF defined as dyspnoea = New York Heart Association (NYHA) III, peripheral oedema, and pulmonary congestion (rales on auscultation or pulmonary vascular congestion on chest radiograph) 2. Age =18 years old 3. Sufficient ultrasound visualization of B-lines

Exclusion criteria

Exclusion criteria: 1. Chronic dialysis or having chronic kidney disease stage IV based on KDIGO criteria 2. Patients required invasive ventilation 3. Pregnant patients 4. Patients with cardiogenic shock defined as a systolic blood pressure less than 90 mmHg with end-organ hypoperfusion or requiring inotropic support 5. Concomitant acute coronary syndrome 6. Pre-existing chronic lung conditions on home oxygen or non-invasive ventilation (NIV) 7. Concomitant pneumonia 8. Severe valvular disease awaiting definitive intervention

Design outcomes

Primary

MeasureTime frame
Length of hospital stay (LOS) days), collected from patient’s electronic medical records, measured from the admission date until the discharge day for each patient

Secondary

MeasureTime frame
90-day re-admission rate collected from patient’s electronic medical records and a follow-up phone call at 90 days post-hospital discharge

Countries

Oman

Contacts

Public ContactAmira Al-Badi
R2056@resident.omsb.org+968 (0)96316695

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026