Single centre randomised controlled trial (RCT) of a chest pain observation unit versus routine care

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN85078221

Enrollment

900

Registered

2004-01-23

Start date

2001-02-05

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular diseases: Heart disease Circulatory System Heart disease

Interventions

1. Chest pain observation unit 2. Standard care

Eligibility

Inclusion criteria

Inclusion criteria: 900 patients attending accident and emergency with a primary complaint of chest pain between 7.00am and 7.00pm.

Exclusion criteria

Exclusion criteria: 1. Electrocardiogram (ECG) abnormality 2. Unstable angina 3. Co-morbidity 4. Less than 25 years 5. Unable to consent

Design outcomes

Primary

Measure	Time frame
Proportion of cases of myocardial infarction (MI) inappropriately sent home by 72 hours after attendance.	—

Secondary

Measure	Time frame
1. Quality of life, health and patients satisfaction at one month 2. Hospital reattendance rates and adverse cardiac event rates at one year and hospital resource usage over one year 3. Quality of life questionnaire (36-item short form health survey [SF-36]) anxiety/depression scales (Hospital anxiety and depression scale [HADS]) and health utility scale (EQ-5D)	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026