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A prospective randomised cross-over trial to examine the effect of auto variable positive airway pressure versus standard non-invasive positive pressure ventilation on stable chronic obstructive pulmonary disease-patients previously established on non-invasive ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN84977419
Enrollment
25
Registered
2006-08-31
Start date
2005-12-15
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease (COPD) Respiratory Chronic Obstructive Pulmonary Disease (COPD)

Interventions

AutoVPAP versus NIPPV

Sponsors

Papworth Hospital NHS Foundation Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Chronic Obstructive Pulmonary Disease (COPD) 2. Forced Expiratory Volume in One second (FEV1) more than 50% predicted value 3. Smoking history more than 20 pack years

Exclusion criteria

Exclusion criteria: 1. Aged over 80 years 2. No other significant lung disease

Design outcomes

Primary

MeasureTime frame
Nocturnal oxygenation

Secondary

MeasureTime frame
Quality of life

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026