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A pragmatic randomised controlled trial of treatments for Idiopathic Intracranial Hypertension

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN84867253
Enrollment
Unknown
Registered
2004-04-23
Start date
2000-04-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Intracranial Hypertension Circulatory System

Interventions

1. Acetazolamide 2. Weight reduction 3. Optic nerve sheath fenestration 4. Ventriculo-peritoneal or lumbo-peritoneal shunts

Sponsors

University of Birmingham (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosis of Idiopathic Intracranial Hypertension (including that caused by medication such as tetracyclines) 2. Willing to give written informed consent 3. Able to complete trial documentation 4. Randomising clinician is uncertain about the treatment the patient should receive

Exclusion criteria

Exclusion criteria: 1. `Idiopathic¿ Intracranial Hypertension caused by cerebral venous sinus thrombosis or chronic neurological conditions (e.g. infections) 2. Contraindication to acetazolamide such as hypokalaemia, hyponatraemia, hyperchloraemic acidosis, severe hepatic impairment, renal impairment, sulphonamide sensitivity 3. Randomising clinician is certain about the treatment the patient should receive

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026