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Starting dose of ultraviolet B to treat psoriasis

A randomised comparison of methods of selecting narrow-band ultraviolet B starting dose to treat chronic psoriasis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN84614024
Enrollment
210
Registered
2009-12-10
Start date
2003-12-15
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

Narrowband ultraviolet B phototherapy: administered as routine except for decision on start dose. The method of deciding first narrowband ultraviolet B dose was randomised: 1. Start dose 70% minimal e

Sponsors

NHS Tayside (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients referred for NB-UVB phototherapy for chronic (defined as present for more than one year) psoriasis (as diagnosed by a dermatologist), from our catchment area

Exclusion criteria

Exclusion criteria: 1. Less than 16 years old 2.On systemic immunosuppressant therapy or retinoids within the preceding three months

Design outcomes

Primary

MeasureTime frame
1. Number of narrowband ultraviolet B treatments to clearance of psoriasis 2. Number of important (uncomfortable or painful) erythema episodes occurring during treatment courses

Secondary

MeasureTime frame
1. Change in Psoriasis Disability Index (Finlay AY, Khan GK, Luscombe DK, Salek MS. Validation of Sickness Impact Profile and Psoriasis Disability Index in Psoriasis. Br J Dermatol. Dec 1990;123(6):751-756.) 2. Change in Psoriasis Area and Severity Index Both outcomes above were measured at baseline before the first UVB treatment, the 15th and the last treatment visit.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 30, 2026