Intracameral voriconazole injection in the treatment of fungal endophthalmitis developed from keratitis

Intracameral voriconazole injection in the treatment of fungal endophthalmitis developed from keratitis: a retrospective non-randomised non-controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN84613089

Enrollment

Registered

2010-01-06

Start date

2005-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fungal endophthalmitis developed from keratitis Eye Diseases Disorders of globe

Interventions

100 µg of voriconazole in 0.1 ml was injected into the anterior chamber using a 30-gauge needle attached to a 1.0 ml regular insulin syringe. Intracameral voriconazole injection was given once a day a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Fungal endophthalmitis from keratitis 2. Anterior chamber shows fungal web, fungal balls or endothelial plaque 3. Culture approved 4. Aged 38 - 78 years, either sex

Exclusion criteria

Exclusion criteria: 1. Bacterial infection 2. Culture negative 3. Fungal infection from other source

Design outcomes

Primary

Measure	Time frame
Clinical observation, checked 1 month and 4 months after treatments	—

Secondary

Measure	Time frame
Checked 1 month and 4 months after treatments: 1. Visual acuity 2. Fungal infiltrate disappearance	—

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026