Is treatment of alcohol dependence equally effective when carried out in primary care as in a specialized alcohol dependence clinic?

Treatment of Alcohol dependence in Primary care - implementation and effects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN84490505

Enrollment

300

Registered

2013-07-09

Start date

2013-10-28

Completion date

Unknown

Last updated

2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol dependence Mental and Behavioural Disorders Mental and behavioural disorders due to use of alcohol

Interventions

Extended brief intervention (psychosocial and/or pharmacological treatment) conducted by either primary care or a specialized clinic for a dependence treatment. Patients are treated f

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Alcohol dependence according to ICD-10 criteria 2. Male and female, >18 years of age 3. Housing in Stockholm municipality

Exclusion criteria

Exclusion criteria: 1. Extensive social problems 2. Withdrawal symptoms 3. Abuse or dependence of other substances apart from alcohol and/or nicotine 4. Severe psychiatric and/or somatic illness 5. Non-Swedish speaking

Design outcomes

Primary

Measure	Time frame
Current primary outcome measures as of 23/08/2013: Change of weekly alcohol consumption measured in grams of alcohol at baseline, defined as 30 days before inclusion, compared to 12 months after start of treatment, defined as 30 days before the 12-month follow-up visit. Comparisons will be made between participants treated in primary care and specialist care. Previous primary outcome measures: 1. Proportion of days with any drinking during treatment and follow-up 2. Proportion of days with heavy drinking during treatment and follow-up Measured at 6 and 12 months following inclusion in study	—

Measure

Time frame

Current primary outcome measures as of 23/08/2013: Change of weekly alcohol consumption measured in grams of alcohol at baseline, defined as 30 days before inclusion, compared to 12 months after start of treatment, defined as 30 days before the 12-month follow-up visit. Comparisons will be made between participants treated in primary care and specialist care. Previous primary outcome measures: 1. Proportion of days with any drinking during treatment and follow-up 2. Proportion of days with heavy drinking during treatment and follow-up Measured at 6 and 12 months following inclusion in study

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Secondary

Measure	Time frame
Current secondary outcome measures as of 23/08/2013: All with baseline measures compared with measures at follow-up 6 and 12 months after start of treatment in the study, except for the first measure with follow-up 6 months after inclusion in the study. 1. Change of weekly alcohol consumption measured in grams of alcohol 2. Change of days with heavy drinking (cut off women > 3/men >4 standard units with 12 grams of alcohol) per week 3. Change of hazardous and harmful drinking 4. Change of degree of alcohol dependence 5. Change of consequences of drinking 6. Change of symptoms of anxiety and depression 7. Change of quality of life 8. Change of levels of carbohydrate-deficient transferring (CDT) 9. Change of levels of aspartate aminotransferase (AST) 10. Change of levels of alanine aminotransferase (ALT) 11. Change of levels of gamma-glutamyltransferase (GGT) Measure at follow-up 6 and 12 months after start of treatment in the study. 12. Satisfaction with treatment Comparisons will be made between participants treated in primary care and specialist care. Previous secondary outcome measures: 1. Severity of dependence 2. Psychiatric health 3. Percieved quality of life 4. Biological markers Measured at 6 and 12 months following inclusion in study	—

Measure

Time frame

Current secondary outcome measures as of 23/08/2013: All with baseline measures compared with measures at follow-up 6 and 12 months after start of treatment in the study, except for the first measure with follow-up 6 months after inclusion in the study. 1. Change of weekly alcohol consumption measured in grams of alcohol 2. Change of days with heavy drinking (cut off women > 3/men >4 standard units with 12 grams of alcohol) per week 3. Change of hazardous and harmful drinking 4. Change of degree of alcohol dependence 5. Change of consequences of drinking 6. Change of symptoms of anxiety and depression 7. Change of quality of life 8. Change of levels of carbohydrate-deficient transferring (CDT) 9. Change of levels of aspartate aminotransferase (AST) 10. Change of levels of alanine aminotransferase (ALT) 11. Change of levels of gamma-glutamyltransferase (GGT) Measure at follow-up 6 and 12 months after start of treatment in the study. 12. Satisfaction with treatment Comparisons will be made between participants treated in primary care and specialist care. Previous secondary outcome measures: 1. Severity of dependence 2. Psychiatric health 3. Percieved quality of life 4. Biological markers Measured at 6 and 12 months following inclusion in study

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Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026