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Calcium supplementation and weight-bearing physical activity: do they have a combined effect on the bone mineral density of pre-pubertal children?

A double blind, randomised controlled trial of the effects of calcium supplementation on bone density, geometry and strength in pre-pubertal gymnasts and healthy controls

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN84437785
Enrollment
86
Registered
2001-03-01
Start date
2002-01-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calcium supplementation and bone mineral density Nutritional, Metabolic, Endocrine Calcium supplementation

Interventions

Gymnasts who participate in greater than 6 hours high intensity gymnastics a week. Sedentary children who participate in less than 2 hours high intensity weight bearing exercise per week.

Sponsors

Action Medical Research (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pre-pubertal children aged 5 - 14 years, either sex 2. Signed parental or guardian consent received 3. Agreement to participate by the child

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

MeasureTime frame
Increase in cortical and trabecular volumetric bone mineral density (vBMD) at the radius and tibia, assessed using peripheral quantitative computed tomography (pQCT). Added 25/01/2010: All outcomes were measured at baseline and 12 months after completing 12 months supplementation.

Secondary

MeasureTime frame
Changes in: 1. Bone geometry at the radius and tibia 2. Lumbar spine 3. Whole body measurements Assessed using peripheral quantitative computed tomography (pQCT) (distal and diaphyseal radius and tibia) and dual energy X-ray absorptiometry (DXA) (lumbar spine and whole body). Added 25/01/2010: All outcomes were measured at baseline and 12 months after completing 12 months supplementation.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026