Kidney disease (KD) Urological and Genital Diseases Kidney disease
Conditions
Interventions
DIMENSION-KD is a observational (i.e. no treatment or intervention) cross-sectional (i.e. a 'snapshot' of participants) study which aims to establish the effect and associations of kidney disease and
Sponsors
University Hospitals of Leicester NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosed kidney disease patients 2. Willing and able to give informed consent and comply with the study protocol 3. Male or female 4. Aged 18 years or above
Exclusion criteria
Exclusion criteria: 1. Age <18 years 2. Any other significant disease or disorder which, in the opinion of the patient’s own clinician, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant’s ability to participate in the study 3. Inability to give informed consent or comply with the protocol for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Investigate the role and differing impact of KD and basic lifestyle factors on patient’s physical function, symptoms, healthcare activation, and muscle function. 2. Qualitatively explore the patient ‘living experience’ of KD and the impact and role of lifestyle on patient QoL, physical functioning, and health status. 3. Explore the association between dietary intake with body composition, physical function/strength, symptoms, and blood markers. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Explore the association between mechanical and viscoelastic characteristics of the quadriceps and bicep muscle with physical functioning. 2. Validate the Biodex dynamometer against the Fysiometer for the assessment of lower limb strength in patients with KD. 3. Further exploratory investigation will take place as necessary/appropriate (i.e. if/when new information becomes available), however all investigation will aim to explore lifestyle-based determinants of physical function, muscle health, and disease management, with a basis that this information will help us guide and design lifestyle-based interventions to improve the important and most pertinent factors. | — |
Countries
England, United Kingdom
Outcome results
None listed