A double blind randomised placebo-controlled trial of amoxycillin and budesonide in patients with acute rhinosinusitis in general practice

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN84277311

Enrollment

240

Registered

2004-01-23

Start date

2001-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ear, nose and throat diseases: Ear, nose and throat diseases Ear, Nose and Throat Acute rhinosinusitis

Interventions

1. Amoxycillin tablets 500 mg twice daily for 10 days versus placebo 2. Budesonide nasal spray 200 µg each nostril once daily for 10 days versus placebo

Eligibility

Inclusion criteria

Inclusion criteria: Patients 16 years or over attending the GP for acute rhinosinusitis, who agree to be randomised.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
The percentage with diary recorded complete resolution of all symptoms (cured) at 14 days.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026