Cerebral palsy Nervous System Diseases Cerebral palsy
Conditions
Interventions
Design: A cross over randomised exposure response experimental study with embedded process evaluation.
Setting: Testing will take place at Oxford Brookes University (OBU), Thames Vall
Sponsors
Oxford Brookes University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. YPwCP aged 10-18 years (primary and secondary special and mainstream schools) 2. Able to participate safely in assessments and brief interrupted sitting MVPA physical activity (with or without support) 3. Gross Motor Function Classification System level I to III 4. Communication Function Classification System level 1 to 3
Exclusion criteria
Exclusion criteria: 1. Children with uncontrolled epilepsy/seizures (stable epilepsy/on medication > 12 weeks) 2. Type 1 and Type 2 diabetes or other glucose intolerance or on medication for such conditions 3. Surgery in previous 6 months 4. Botulinum toxin treatment in previous 6 weeks 5. Serial casting in previous 3 months (or planned) 6. Contraindications to physical training 7. Participants who are considered too cognitively impaired to participate in the trial, as determined by consultants 8. Children with spinal instability or other spinal problems that could inhibit them from participating safely 9. Children who are on any form of steroids, anti anxiety/depression drugs, birth control, beta-blockers, statin, adrenaline, HIV or Hepatitis C medications will be excluded from the intervention as these medications can affect the readings during the OGTT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in executive functioning from the start to the end of the session. There are two areas of executive functioning the research aims to focus on: inhibitory control which targets speed and accuracy of the participants, and working memory and attention task. Tasks will be performed before and at the end of the session intervention periods. Timepoint(s): Assessed during the 3 (out of 4) sessions (not at baseline) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Anthropometrics: height, weight, BMI, sitting height, age, leg length, shoe size plus the GMFCS (gross motor function classification system) level: 1/2/3/4/5 (if needed), measured at baseline visit 2. Blood pressure and heart rate measured at every visit (4 in total) 3. 10 m walk test and Sit to Stand test measured at baseline visit 4. Strength (grip and leg) measured at baseline visit 5. Fitness measured using PAR-Q physical activity readiness questionnaire and V02 exercise performance test at baseline visit 6. Physical activity measured using accelerometry at every visit and for the next 7 days after the visit day 7. Blood glucose monitored by scanning the Freestyle Libre sensor at the three intervention visits (visit 2, 3 and 4) 8. Salivary insulin measured using saliva samples at the three intervention visits (visit 2, 3 and 4) 9. Movement monitored using activity monitor activPAL at the three intervention visits (visit 2, 3 and 4) 10. Questionnaires: Habit Dietary HBSC and 24-hour dietary recall at the three intervention visits (visit 2, 3 and 4) , physical activity questionnaire at one of the intervention visits (visit 2, 3 or 4) , Child Utility 9D questionnaire at one of the intervention visits (visit 2, 3 or 4) 11. Process evaluation questionnaire (Child/Parent) at the last intervention visit | — |
Countries
England, United Kingdom
Contacts
Public ContactShelly Coe
Outcome results
None listed