Moderated osteoarthritis of the knee joint Musculoskeletal Diseases
Conditions
Interventions
Patients will be placed on the radiolucent table at the Department of Interventional Radiology in a supine position with a bolster under the knee to produce 30? of flexion
this position flattens the suprapatellar joint space, thus minimizing needle trespass, and also allows for an unobstructed lateral view of the knee. The treated knee will be draped and sterilized in a
Sponsors
University of Patras
Eligibility
Sex/Gender
All
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients of either sex will participate in the clinical trial as long as they have: 1. The NICE clinical criteria of primary knee OA for one or both knees: 1.1. Age >45 years 1.2. Activity-related joint pain 1.3. No morning joint stiffness or morning stiffness that lasts no longer than 30 minutes 2. Radiological confirmation of knee arthritis (grade =2) according to the Kellgren and Lawrence classification 3. Chronic knee pain for a minimum duration of 6 months 4. Pain intensity =4 on the (NRPS) 5. Lack of pain relief from conventional therapy, including nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, muscle relaxants, oral steroids, physical therapy, and intra-articular injection therapy. 6. The ability to communicate in Greek
Exclusion criteria
Exclusion criteria: 1. inflammatory or post-traumatic knee arthritis 2. Patients who have received CRFA treatment in the past 3. Injection of hyaluronic acid or corticosteroid within the previous 3 months 4. Significant structural deformities affecting locomotion and knee function aside from osteoarthritis and which might cause chronic knee pain 5. Body mass index =40 kg/m² 6. Uncontrolled serious disease (cancer, diabetes, end-stage heart disease etc) 7. Unstable psychiatric illness 8. Coagulopathy or bleeding disorders 9. Active systemic or local infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain associated with knee OA measured using the Numerical Rating Pain Scale (NRPS) at 1, 3, and 6-month post-intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety and tolerability of the interventions, and patient’s clinical outcome measured using the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR), the Oxford Knee Score (OKS), the SF-12 and the Forgotten Joint Score (FJS) at 1-, 3- and 6-months post-intervention | — |
Countries
Greece
Contacts
Public ContactAndreas Panagopoulos
Outcome results
None listed