Debridement options for the treatment of the forearm and hand partial thickness dermal burns

Comparison of enzymatic, mechanical and autolytic debridement methods efficiencies for the treatment of the forearm and hand deep dermal burns

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN84005357

Enrollment

Registered

2016-12-16

Start date

2014-04-01

Completion date

Unknown

Last updated

2017-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Forearm and hand deep dermal partial thickness burns Injury, Occupational Diseases, Poisoning

Interventions

Participants are randomised into four treatment groups: 1. Standard treatment – gauze dressings with silver sulfadiazine (SSD) 1% ointment (Sulfargin, Grindeks AS, LV) applied once daily on burn wound

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients aged from 18 to 65 2. Non-extensive burns (total body surface area, TBSA <30%) 3. Forearms and hands deep dermal partial thickness burns (2B°, LDI evaluation: 260 - 600PU) 4. Agreed with trial protocol and signed the consent form

Exclusion criteria

Exclusion criteria: 1. Patients with superficial partial thickness and full thickness forearms and hands burns (2Aº, 3º; LDI evaluation: 600PU) 2. Patients with known pregnancy (pregnancy test was performed for all female patients) 3. Vulnerable persons (psychiatric diagnosis)

Design outcomes

Primary

Measure	Time frame
Measured at 3, 7, 14 and 21 days post burn: 1. Burn wound size, estimated by covering it with transparent film and counting square centimeters with a ruler 2. Pain, measured with the Visual Analog Scale (VAS) 10 minutes after dressings have been changed 3. Clinical wound conditions: persistence of necrosis, amount of fibrin, granulation tissue, and epithelialization process, evaluated as a percentage from whole wound area by the same physician according to the study protocol measurement parameters 4. Burn wound contamination, assessed using the Levine wound-swabbing technique	—

Measure

Time frame

Measured at 3, 7, 14 and 21 days post burn: 1. Burn wound size, estimated by covering it with transparent film and counting square centimeters with a ruler 2. Pain, measured with the Visual Analog Scale (VAS) 10 minutes after dressings have been changed 3. Clinical wound conditions: persistence of necrosis, amount of fibrin, granulation tissue, and epithelialization process, evaluated as a percentage from whole wound area by the same physician according to the study protocol measurement parameters 4. Burn wound contamination, assessed using the Levine wound-swabbing technique

—

Secondary

Measure	Time frame
Measured at six months follow-up: 1. Quality of post burn scars, assessed using the Vancouver Scar Scale (VSS) 2. Functional recovery, assessed using the Disabilities of the Arm, Shoulder and Hand (DASH) outcome measure official Lithuanian translation	—

Countries

Lithuania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026