Effects of intestinal helminth infections in early childhood on immune response, inflammation, anaemia and malnutrition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN83988447

Enrollment

2500

Registered

2005-07-22

Start date

2004-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaemia, protein-energy malnutrition, anorexia Haematological Disorders Anaemia

Interventions

Double blind Randomised Controlled Trial (RCT) of mebendazole versus an identical-looking but inert placebo.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Six to 24 months of age 2. Informed consent 3. Residing in selected communities based on geographic catchment area

Exclusion criteria

Exclusion criteria: 1. Haemoglobin less than 70 g/l 2. Refusal of informed consent

Design outcomes

Primary

Measure	Time frame
1. Haemoglobin less than 70 g/l 2. Mid upper arm circumference less than -2 Z scores of international reference 3. Maternal report of anorexia	—

Secondary

Measure	Time frame
1. Weight-for-height less than -1 Z scores of international reference 2. Height-for-age less than -2 Z scores on international reference 3. Inflammation	—

Countries

Tanzania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026