Machine perfusion preservation versus cold storage of cadaveric kidneys for transplantation

Conditions

Kidney insufficiency Surgery

Treckmann J, Moers C, Smits JM, Gallinat A, Maathuis MH, van Kasterop-Kutz M, Jochmans I, Homan van der Heide JJ, Squifflet JP, van Heurn E, Kirste GR, Rahmel A, Leuvenink HG, Pirenne J, Ploeg RJ, Paul A.

2011-02-17151 citations

10.1111/j.1432-2277.2011.01232.x

Machine perfusion or cold storage in deceased-donor kidney transplantation.

Moers C, Smits JM, Maathuis MH, Treckmann J, van Gelder F, Napieralski BP, van Kasterop-Kutz M, van der Heide JJ, Squifflet JP, van Heurn E, Kirste GR, Rahmel A, Leuvenink HG, Paul A, Pirenne J, Ploeg RJ.

2009-01-01734 citations

10.1056/nejmoa0802289

Interventions

One kidney of each donor is randomised to machine perfusion, the other kidney will be cold stored

Eligibility

Inclusion criteria

Inclusion criteria: Every deceased donor older than 15 years will be included

Exclusion criteria

Exclusion criteria: Combined transplantations

Design outcomes

Primary

Measure	Time frame
Delayed graft function defined by necessity of dialysis in the first 7 days post transplant	—

Secondary

Measure	Time frame
1. Decrease of creatinine 2. Rejection rates 3. Graft survival 4. Economics	—

Countries

Germany, Netherlands

Outcome results

None listed