Improving the mental health and wellbeing of people affected by leprosy or Buruli ulcer in Nigeria

Conditions

Mental health and quality of life of persons affected by leprosy or Buruli ulcer Mental and Behavioural Disorders

Eze CC, Ekeke N, van Brakel W, Ossai EN, Henry P, Onyima-Esmai A, Nwafor CC, Murphy-Okpala N, Meka A, Ezeakile O, Njoku M, Iyama FS, Anyaike C, Egbule D, Chukwu J.

2025-10-30

10.1371/journal.pone.0327741

Consort checklist 2010.

Chinwe C. Eze (8787503), Ngozi Ekeke (3502973), Wim van Brakel (155684), Edmund Ndudi Ossai (10834364), Precious Henry (18840731) et al. (15 authors)

OPAL (Open@LaTrobe) (La Trobe University)2025-10-30

10.1371/journal.pone.0327741.s001

Inclusivity in global research.

Chinwe C. Eze (8787503), Ngozi Ekeke (3502973), Wim van Brakel (155684), Edmund Ndudi Ossai (10834364), Precious Henry (18840731) et al. (15 authors)

OPAL (Open@LaTrobe) (La Trobe University)2025-10-30

10.1371/journal.pone.0327741.s002

A Cluster Randomized Trial for Improving Mental Health and Well-Being of Persons Affected by Leprosy or Buruli Ulcer in Nigeria

Ngozi Ekeke, Edmund Ndudi Ossai, Saskia Kreibich, Amaka Onyima, Joseph Chukwu et al. (10 authors)

International Journal of Mycobacteriology2022-04-016 citations

10.4103/ijmy.ijmy_247_21

Interventions

The study proposes a holistic, community-oriented approach for improving access and utilization of mental health services through interventions using holistic approach work synergistically to reduce m

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Any person affected by leprosy or Buruli ulcer 2. All people affected by leprosy or Buruli ulcer registered for treatment from 2014 up to 1 year before the end of the intervention 3. Participants aged between 15 to 65 years registered for treatment

Exclusion criteria

Exclusion criteria: 1. Refusal to give consent 2. Pregnant women 3. Patients who need urgent medical attention 4. Patients unable to communicate clearly

Design outcomes

Primary

Measure	Time frame
Mental health status (especially, depression and generalized anxiety disorder) and the quality of life measured using PHQ-9, GAD-7 and WHOQOL-BREF at baseline (before intervention) and repeated after 2 years of intervention	—

Secondary

Measure	Time frame
1. Mental well-being of patients measured using the Warwick Edinburgh Mental Well-being Scale (WEMWBS) at baseline (before intervention) and repeated after 2 years of intervention 2. Self-stigma of leprosy patients measured with SARI Stigma Scale at baseline (before intervention) and repeated after 2 years of intervention 3. Social inclusion of leprosy patients by community members measured using the Social Distance Scale (SDS) at baseline (before intervention) and repeated after 2 years of intervention	—

Measure

Time frame

1. Mental well-being of patients measured using the Warwick Edinburgh Mental Well-being Scale (WEMWBS) at baseline (before intervention) and repeated after 2 years of intervention 2. Self-stigma of leprosy patients measured with SARI Stigma Scale at baseline (before intervention) and repeated after 2 years of intervention 3. Social inclusion of leprosy patients by community members measured using the Social Distance Scale (SDS) at baseline (before intervention) and repeated after 2 years of intervention

—

Countries

Nigeria

Contacts

Public ContactNgozi Ekeke

ngozi.ekeke@dahw.org+234 (0)8035076274

Outcome results

None listed