Specialty: Reproductive health and childbirth, Primary sub-specialty: Reproductive and sexual medicine Pregnancy and Childbirth Pre-eclampsia
Conditions
Interventions
All participants to attend the 2 study visits (at 11-13 weeks gestation and 19-24 weeks gestation). The final, pregnancy outcome data is retrieved from patient notes so no participant visit is require
Sponsors
Delegated to University College London Comprehensive Clinical Trials Unit (UCL CCTU) by Kings College London
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or over 2. Singleton pregnancy 3. Live fetus at 11-13 weeks' gestation 4. Informed and written consent
Exclusion criteria
Exclusion criteria: 1. Women who are severely ill 2. Those with learning difficulties 3. Those with a serious mental illness 4. Pregnancies complicated by major fetal abnormality identified at 11-13 weeks of gestation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy (false positive and true positive frequencies) of screening for pre-eclampsia using the Bayes theorem based method is measured as the rate of pre-eclampsia, determined using medical note review within one month of birth. | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection rate of pre-eclampsia is measured through medical note review within one month of birth. | — |
Countries
England, United Kingdom
Outcome results
None listed