Psychosis Mental and Behavioural Disorders Psychosis
Conditions
Interventions
For participants with carers:
1. Cognitive behavioural therapy (CBT) and treatment as usual (TAU)
2. Family intervention (FI) and TAU
3. TAU only
For participants with no carers:
1. CBT and TAU
2.
Sponsors
King's College London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants are recruited from identified psychiatric teams in four NHS Trusts. Entry criteria: 1. Current diagnosis of psychosis 2. Non-affective (International Statistical Classification of Diseases and Related Health Problems, Tenth edition [ICD-10], F20) 3. Aged 18 to 65 years, either sex 4. Second or subsequent episode, which started not more than three months before entry 5. Rated at least four (moderate severity) on the Positive and Negative Syndrome Scale (PANSS) on at least one positive psychotic symptom
Exclusion criteria
Exclusion criteria: Added 03/03/2009: 1. Primary diagnosis of alcohol or substance dependency, organic syndrome or learning disability 2. Inadequate command of English to engage in psychological therapy 3. Unstable residential arrangements and so unlikely to be available for therapy and/or assessments over period of trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse and days in hospital over 24 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pattern of symptom change (PANSS total scores and subscale scores, Psychotic SYmptom RATing Scales [PSYRATS], Beck Depression Inventory [BDI], Beck Anxiety Inventory [BAI]) over 12 and 24 months 2. Social functioning (time budget) at 24 months | — |
Countries
United Kingdom
Outcome results
None listed