Stroke Nervous System Diseases
Conditions
Interventions
Current interventions as of 15/01/2025:
We will conduct a pilot evaluation of a novel Magnetic Detection Electrical Impedance Spectroscopy (MDEIS) and Microwave Radar (MWR) device to determine its po
Sponsors
Northern Care Alliance NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Stage A: Healthy volunteers: 1. Aged 18 years or over 2. No significant health problems deemed by the investigator as likely to interfere with the study procedures or data analysis (e.g. previous or existing cerebral pathology) 3. Able to provide informed consent Stage B: Stroke patients: 1. Aged 18 years or over 2. Diagnosis of supratentorial ischaemic stroke or spontaneous intracerebral haemorrhage, within 72 h of symptom onset 3. Research MR scan can be performed within 5 days of admission 4. Likely to be able to safely complete study procedures, in the opinion of the lead clinical investigator or delegated clinical investigator
Exclusion criteria
Exclusion criteria: Stage A: Healthy volunteers: Any intracranial or extracranial metallic implant Stage B: Stroke patients: 1. Any intracranial metallic implant 2. Any extracranial metallic implant 3. Any contraindication to magnetic resonance scanning 4. Pre-existing intracranial pathology likely to interfere with measurements (e.g. previous stroke, tumour) 5. Any known condition which, in the opinion of the researcher, is likely to interfere with the planned recordings 6. Patient has undergone a neurosurgical procedure during the current admission, or this is planned within the next 24 h 7. Female patient who may be pregnant or is breastfeeding 8. Known allergy to electrodes 9. Any other significant disease or disorder which, in the opinion of the PI or his delegate, may put the participant at risk because of participation in the study, or may influence the result of the study, or the participant’s ability to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asymmetry index, determined from the microwave and MDEIS device, measured at a single timepoint in healthy volunteers and at 1 to 5 days after symptom onset in stroke patients | — |
Secondary
| Measure | Time frame |
|---|---|
| Transimpedance (Z), determined from the MDEIS device, measured at a single time point in healthy volunteers and at 1 to 5 days after symptom onset in stroke patients | — |
Countries
England, United Kingdom
Outcome results
None listed