Diagnosis and management of airways disease Respiratory
Conditions
Interventions
BREATHE is a single-centre, prospective longitudinal cohort study of patients who are referred to the Complex Airways Clinic at North Bristol NHS Trust (NBT). It is a platform which will include diffe
Sponsors
North Bristol NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Participant is willing and able to give informed consent for participation in the study 2. Known or suspected airways disease
Exclusion criteria
Exclusion criteria: 1. Participants who lack the capacity to consent for themselves 2. Aged below 16 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical and biological characteristics of patients with suspected or known airways disease, described using standard care clinical data over a 5-year period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Airways disease phenotypes and impact on disease outcomes assessed using standard care data collected over a 2-year period for each patient 2. Impact of the multidimensional clinical assessment on disease outcomes assessed by reviewing MDT outcomes over the 5-year study period 3. Response to treatment offered as part of the Complex Airways Service, assess by reviewing clinical and patient-reported outcomes over the 5-year study period 4. The prevalence of asthma mimics in this population, including inducible laryngeal obstruction (ILO), assessed by reviewing ILO diagnosis and clinical and patient-reported outcomes over a 2-year funded study period | — |
Countries
England, United Kingdom
Contacts
Public ContactCaitlin Morgan
Outcome results
None listed