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UK Hepatic Artery Pump Trial Two: Continuous Hepatic-Artery Infusion for Palliation in Colorectal Liver Metastases

UK Hepatic Artery Pump Trial Two: Continuous Hepatic-Artery Infusion for Palliation in Colorectal Liver Metastases

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN83441783
Enrollment
Unknown
Registered
2002-08-19
Start date
1990-01-01
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer of Colon, Liver, Rectum Cancer Colon, Liver, Rectum

Interventions

1. Regimen A: Intra-hepatic continuous infusion of floxuridine for 5 days followed by systemic 5-fluorouracil and folinic acid for 5 days delivered via an arterial port-a-cath. 2. Regi

Sponsors

Colon Cancer Concern (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Aged <75 years 2. Colorectal liver metastases, less than 45% liver involvement as assessed by Computed Tomography (CT) scan 3. Karnofsky score more than 80% 4. Normal Bilirubin level 5. No prior chemotherapy

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026