Mild and moderate diabetes mellitus of type II (age-related) Nutritional, Metabolic, Endocrine
Conditions
Interventions
Sucontral® D Capsules, Harras Pharma Curarina, Munich, with 100 mg of a dry concentrate per capsule (extraction solvent ethanol 32°%) from the bark of the Central American plant Hintonia latiflora (SE
Sponsors
Gehrlicher Pharmazeutische Extrakte GmbH (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetics 2. Between the ages of 45 and 80 3. Neither oral antidiabetic agents nor insulin were used 4. Prescribed diet had led to stable but not nearly normoglycaemic values As a condition for inclusion in the study, diabetic symptoms must have existed for a period of at least 12 months. The values for fasting blood sugar had to be in the range from 7-14 mmol/l (normal value: 3.9-5.4 mmol/l).
Exclusion criteria
Exclusion criteria: To be excluded were patients for whom there was a doubt about the reliability with respect to the adherence to the dietetic guidelines (e.g., with regard to alcohol consumption). Other exclusion reasons were severe diabetic symptoms, progressive life-threatening diseases, hepatic dysfunction or renal insufficiency (deviations of GOT, ?GT and AP of more than twice the normal value, serum creatinine > 130 µmol/l), hypoglycaemic crises not noticed in time, retinopathy, pregnancy, malignant tumours and/or drug or alcohol dependence in the medical history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar and postprandial blood sugar (two hours after food intake) as well as blood pressure and body weight were recorded at monthly intervals. The HbA1c value was recorded after three and six months as were the liver values and blood lipids. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Safety laboratory including liver function tests 2. Physical symptoms 3. Adverse events | — |
Countries
Slovakia
Outcome results
None listed