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A program to optimize the quality of antibiotic use within the hospital - impact on antibiotic consumption, cost savings and bacterial resistance

A PRogram to Optimize the quality of Antibiotic use within the hospital - impact on antibiotic consumption, cost savings and bacterial resistance: a randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN83234896
Enrollment
816
Registered
2012-05-08
Start date
2007-01-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients on antibiotic therapy Infections and Infestations

Interventions

Patients with 3 day antibiotic treatment will be identified by the pharmacy service daily from Monday to Friday. Once checked the inclusion criteria, there will be the randomization stratified by clin

Sponsors

Training and Research Institute, Marqués de Valdecilla (Spain)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients: The reference population is composed of patients admitted in the Hospital Universitario Marqués de Valdecilla with antimicrobial treatment prescribed by their responsible doctors for more than three days. The clinical services/units in which the study will be realized will comply with the following criteria for inclusion: 1. Stability in the physicians who participate in the study 2. Stability in the number of beds and type of assisted 3. Agreement by doctors who work in them to participate in the study

Exclusion criteria

Exclusion criteria: 1. Pediatric patients 2. Patients with terminal chronic renal failure (on dialysis) 3. Patients with oral antibiotic treatment 4. Antibiotic treatment already prescribed by the Infectious Diseases Unit Patients whose antibiotic has been prescribed by a member of the Infectious Diseases Unit as part of the usual care task shall be excluded from the study

Design outcomes

Primary

MeasureTime frame
1. To know the current situation of antibiotic use in the Valdecilla Hospital 2. To evaluate the impact of an intervention designed to optimize the antibiotic consumption and cost, as well as the incidence of bacterial resistance in some hospitalization units

Secondary

MeasureTime frame
1. To analyze the impact of the intervention on the microbiological and clinical prognosis of patients, as well as half of them stay 2. To investigate the adhesion of medical intervention and the impact of such adherence on the microbiological and clinical prognosis of patients 3. To investigate if the results obtained with the intervention are maintained over time

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 25, 2026