The effect on clinical outcome of glutamine supplementation of parenteral nutrition in the surgical newborn infant

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN83168963

Enrollment

250

Registered

2003-04-30

Start date

2002-04-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical newborn infants on parenteral nutrition Surgery Parenteral nutrition

Interventions

The treatment group will receive glutamine-supplemented parenteral nutrition. The control group will receive isonitrogenous parenteral nutrition. All patients will have data collected once a week on

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Surgical infants below the age of 3 months, either sex 2. Require parenteral nutrition 3. Have received less than 5 days of parenteral nutrition already

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. Infection: episodes of sepsis and septicaemia, timing of sepsis and septicaemia 2. Intestinal function: time to full enteral feeding and time on (days)	—

Secondary

Measure	Time frame
1. Growth 2. Nutrient intake 3. Biochemical measures of hepatic function	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 26, 2026