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The effectiveness of regular home use of photodynamic therapy for controlling oral plaque in healthy adults

The effectiveness of regular home use of photodynamic therapy for controlling oral plaque in healthy adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN83029100
Enrollment
30
Registered
2025-03-28
Start date
2024-02-18
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental plaque Oral Health

Interventions

The study is conducted at the University of Tartu, Institute of Dentistry (Tartu, Estonia) as part of dental students’ academic research. All participants provided written informed consent prior to en

Sponsors

Koite Health Oy
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Good oral hygiene, as evidenced by a subjective report of brushing their teeth twice a day and flossing daily 2. No comorbidities 3. Minimal supragingival calculus in the lower front

Exclusion criteria

Exclusion criteria: 1. Concomitant disease 2. Daily mouthwash use (chlorhexidine 0.12% or 0.2%) 3. Gum disease (gingivitis or periodontitis) 4. Candidiasis 5. Daily treatment with medication other than oral contraceptives 6. Presence of subgingival calculus 7. Active caries on the buccal, lingual, or occlusal surface 8. Non-student status 9. Pregnancy 10. Breastfeeding

Design outcomes

Primary

MeasureTime frame
Plaque levels measured using the Green-Vermilion Plaque Score from clinical photographs taken at Visit 1 (Week 0), Visit 2 (Week 2), Visit 3 (Week 4), and Visit 4 (Week 6).

Secondary

MeasureTime frame
Bacterial composition in the gingival sulcus measured using 16S PCR analysis of bacterial samples collected from the gingival pocket at Visit 1 (Week 0), Visit 2 (Week 2), Visit 3 (Week 4), and Visit 4 (Week 6)

Countries

Estonia

Contacts

Public ContactMikko Kylmänen
mikko.kylmanen@koitehealth.com+358 (0)407245934

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026