Effect of acupuncture treatment on Vascular Cognitive Impairment, No Dementia

Effect of acupuncture treatment on Vascular Cognitive Impairment, No Dementia: a multi-center, randomized, controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN82980206

Enrollment

216

Registered

2014-01-17

Start date

2013-07-01

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vascular cognitive impairment not dementia(VCIND) Mental and Behavioural Disorders

Interventions

All participants will be randomized to two different groups: 1. Acupuncture group: this group of patients will receive two acupuncture sessions per week for 3 months. 2

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 55-85 years, either sex 2. Hachinski score =7 3. Evidence of vascular lesions on neuroradiology 4. Fluency in language sufficient to reliably complete all study assessments 5. Mini-Mental State Examination (MMSE) score >dementia threshold corrected based on educational year (>17 scores, >20 scores and >24 scores for 0, =6, and>6 educational years, respectively) 6. Montreal Cognitive Assessment (MoCA) 12 educational years (or <25 scores for=12 educational years) 7. Written and informed consent

Exclusion criteria

Exclusion criteria: 1. History of mental diseases (e.g., schizophrenia, serious anxiety and depression) 2. Patients with Alzheimer's disease, Parkinson's disease, frontotemporal dementia or Huntington's disease 3. Patients with epilepsy and/or ever having antiepileptic drugs 4. Presence of serious heart diseases, kidney diseases or liver diseases

Design outcomes

Primary

Measure	Time frame
The cognitive section of the Alzheimer Disease Assessment Scale (ADAS-Cog) will be assessed at baseline, the end of treatment and 3 months after the end of treatment.	—

Secondary

Measure	Time frame
1. Clock drawing test (CDT) will be assessed at baseline, the end of treatment and 3 months after the end of treatment. 2. Ability of daily living (ADL) and instrumental activities of daily living scale (IADL) will be assessed at baseline, the end of treatment and 3 months after the end of treatment. Participants will report adverse events they experience, including discomfort or bruising at the sites of needle insertion, nausea, or feeling faint after each acupuncture treatment. Adverse drug reactions like nausea and vomiting, dizziness, dry mouth and itching will also be recorded.	—

Measure

Time frame

1. Clock drawing test (CDT) will be assessed at baseline, the end of treatment and 3 months after the end of treatment. 2. Ability of daily living (ADL) and instrumental activities of daily living scale (IADL) will be assessed at baseline, the end of treatment and 3 months after the end of treatment. Participants will report adverse events they experience, including discomfort or bruising at the sites of needle insertion, nausea, or feeling faint after each acupuncture treatment. Adverse drug reactions like nausea and vomiting, dizziness, dry mouth and itching will also be recorded.

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Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026