EXERcise and changes in executive functions and pre-frontal BRAIN activity during walking

Pre-frontal brain activity during walking and executive functions following training: a functional near-infrared spectroscopy (fNIRS) study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN82949128

Enrollment

Registered

2014-03-11

Start date

2013-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Video-exergame training intervention in elderly Not Applicable

Interventions

Participants are randomised to one of two groups: Intervention Group: Receives a progressive dance video game training performed during 30 minutes, three times per week, on dance pads. The program las

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 65 years or older 2. Living independently or in a retirement home 3. Being able to walk 10 minutes without a break on a treadmill 4. Being healthy (self-reported) 5. Having given written informed consent

Exclusion criteria

Exclusion criteria: 1. Individuals who reported more than one serious health complaint (e.g. recent heart attack, uncontrolled diabetes or uncontrolled hypertension) 2. Individuals who reported diagnosis of Alzheimer's disease, dementia, or recent head injuries

Design outcomes

Primary

Measure	Time frame
Near-infrared spectroscopic (NIRS) imaging to assess bilateral increase of oxygenated hemoglobin (oxyHb) in the prefrontal cortex during treadmill walking	—

Secondary

Measure	Time frame
1. Cognitive functioning (shifting, inhibition and updating): paper & pencil test / measured at baseline and three months 2. Short physical performance battery (SPPB): physical performance test / measured at baseline and three months	—

Countries

Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026