Stroke-type neurosyphilis Infections and Infestations
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Positive serum and cerebrospinal fluid (CSF) Treponema pallidum particle agglutination 2. CSF white blood cell count >5/µL or elevated protein (>0.45 g/L) 3. Imaging-confirmed cerebral infarction (computed tomography [CT] or magnetic resonance imaging [MRI]) 4. Clinical presentation consistent with acute stroke (hemiparesis, aphasia, etc). All participants had neurological deficits with a National Institutes of Health Stroke Scale (NIHSS) score =5.
Exclusion criteria
Exclusion criteria: 1. Comorbid major neurological disorders 2. Contraindications to HBO therapy, TUS-NMES or acupuncture 3. Pregnancy or breastfeeding 4. Inability to comply with rehabilitation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurological recovery measured using the National Institutes of Health Stroke Scale (NIHSS) at 28 days;Functional independence measured using the Barthel Index of Activities of Daily Living at 28 days | — |
Countries
China