Digestive System: Liver disease Digestive System Liver disease
Conditions
Interventions
Please note that the above start and end dates of this trial were amended on 19/09/2007 due to reasons stated in the hypothesis above. The previous dates were:
Anticipated start date: 26/10/2004
Antic
Sponsors
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Eligibility
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 19/09/2007: 1. Potential research participants will be identified prospectively from all those admitted electively for transplant assessment to the University Hospital Birmingham over a one year period 2. They will be approached on the morning of admission to hospital. They will be given a patient information leaflet and have an opportunity to ask questions. Consent will not be taken at this time 3. Echocardiograms for pre-transplant assessment are performed on a Monday afternoon. Before the start of the test potential research participants will be approached and given an opportunity to ask further questions. At their satisfaction, they will be asked to sign a consent form if willing to participate 4. Patients electively admitted to UHB Liver Unit for assessment as to suitability for liver transplantation Previous inclusion criteria: Potential research participants will be all patients electively admitted to the Liver Transplantation Programme of the University Hospital Birmingham over a 6 month period from 01/10/2004 for pretransplant assessment. Prospective participants will be identified by review of elective admission lists, and will be approached by one of the investigators (RS) on the morning of admission to hospital. At this time they will be given the relevant information sheet and have an opportunity to ask questions. Consent will not be taken at this time. The echocardiograms are performed later that day, and before the test patients will again have the opportunity to ask questions. The consent form will then be signed at this time if the patient is willing to participate.
Exclusion criteria
Exclusion criteria: Not provided at time of registration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess the prevalence of right to left transpulmonary shunting in patients with advanced liver disease awaiting liver transplantation using transthoracic echo with agitated saline 2. Is there a difference in the prevalence of right to left shunting detected by transthoracic echo with agitated saline in supine and sitting positions | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration. | — |
Countries
United Kingdom
Outcome results
None listed