Cancer: Breast Cancer Malignant neoplasm of breast
Conditions
Interventions
Test intervention vs standardized intervention
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female patients undergoing wide local excision determined by standard criteria for the management of needle biopsy-diagnosed DCIS, or clinical stage 1 or 2 breast cancer 2. Tumour <3cm, have not had previous periareolar incisions or surgical biopsy in the same quadrant as the target lesion, have intact nipples, have an ECOG score of 0-1 3. Able to give consent
Exclusion criteria
Exclusion criteria: Subjects may not participate in the clinical trial if they meet ANY of the following criteria: 1. Currently pregnant within the past 6 months 2. Currently lactating or lactated within the past 6 months 3. Have received chemotherapy within the past 6 months 4. Have an active infection in the breast 5. Have silicone injections or breast implants (pre-pectoral) that disrupt the ductal architecture of the breast 6. Have prior breast surgery that may cause the ductal system not to communicate with the nipple, as determined by the clinician 7. Be unwilling or unable to provide written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duct endoscopy assisted determination of excision margins in breast conservation surgery and its effect on re-excision rates. | — |
Secondary
| Measure | Time frame |
|---|---|
| Added September 2008: laboratory studies on the ductal lavage material obtained. | — |
Countries
United Kingdom
Outcome results
None listed