Blood pressure control and recovery in hemodialysis patients Circulatory System
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnostic criteria for hypertension during dialysis, that is, the blood pressure increased by more than 15 mmHg during dialysis 2. Aged between 18 and 75 years old, with good overall health status 3. Demonstrating good treatment compliance and being able to actively cooperate with the doctor's treatment and guidance 4. The weekly dialysis time was 9 - 12 hours, the KT/V value was at least 1.2, and the hemoglobin (Hb) level was between 10 - 13 g/dL 5. Being able to accurately measure blood pressure in the upper limbs
Exclusion criteria
Exclusion criteria: 1. Patients whose blood pressure could only be measured in the lower limbs 2. Patients with mental disorders or other diseases that affected their cooperation in the study 3. Patients with other serious diseases that might affect the study results
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Blood pressure measured using the blood pressure monitoring module on the dialysis machine before dialysis, at 1, 2, and 3 hours during dialysis, and after dialysis 2. Quality of life measured using the Kidney Disease and Treatment-related Quality of Life (KDTA) and the general health-related quality of life (SF-36) scales before and 12 weeks after the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting venous blood was collected from the elbow to measure hemoglobin (Hb), inflammation markers (IL-6, CRP), nutritional indicators (ALB), homocysteine (Hcy), Parathyroid hormone (PTH) and dialysis adequacy (KT/V) before and 12 weeks after the intervention. 1. Hb measured using advanced photoelectric detector 2. CRP measured using chemiluminescence 3. IL-6 measured using enzyme-linked immunosorbent assay (ELISA). 4. ALB measured using ultraviolet spectrophotometer 5. HCY measured using radioenzyme assay 6. PTH measured using fluorescent immunochromatography | — |
Countries
China