Prognostic value of excessive perineal descent for the surgical outcome of obstructed defecation syndrome

Impact of excessive perineal descent on surgical outcomes in patients with obstructed defecation syndrome: a multicenter retrospective case-control study comparing long-term outcomes of patients undergoing surgical correction of rectal and urogenital abnormalities

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN82669637

Enrollment

495

Registered

2025-01-22

Start date

2024-10-01

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructed defecation syndrome (ODS) Digestive System

Interventions

During defecography and dynamic pelvic MRI, key parameters assessed will include the presence and size of rectocele, recto-rectal and recto-anal intussusception, colpocele, uterocele, enterocele, sigm

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged >18 years 2. Clinically assessed preoperatively using the Obstructed Defecation Syndrome-Score (ODS-S) 3. Evaluated preoperatively with imaging studies (X-ray defecography or dynamic pelvic MRI) 4. Underwent postoperative clinical evaluation at least 3 years after surgery using the ODS-S

Exclusion criteria

Exclusion criteria: 1. Are aged <18 years 2. Did not undergo the required preoperative imaging studies (X-ray defecography and/or dynamic pelvic MRI) 3. Were not evaluated pre- and postoperatively using the ODS-S 4. Had prior anorectal surgery 5. Had a clinical follow-up shorter than 3 years after surgery

Design outcomes

Primary

Measure	Time frame
Impact of excessive perineal descent (PD) on the medium- and long-term outcomes of surgery for obstructed defecation syndrome (ODS), measured by comparing the prevalence of excessive perineal descent (cm) in patients with ODS-S (Obstructed Defecation Syndrome-Score) > 9 (considered as failure of surgery) and < 9 (considered as success of surgery) at the 3-year follow-up point after surgery. The prevalence of excessive perineal descent will be compared between groups using the Chi-square test.	—

Measure

Time frame

Impact of excessive perineal descent (PD) on the medium- and long-term outcomes of surgery for obstructed defecation syndrome (ODS), measured by comparing the prevalence of excessive perineal descent (cm) in patients with ODS-S (Obstructed Defecation Syndrome-Score) > 9 (considered as failure of surgery) and < 9 (considered as success of surgery) at the 3-year follow-up point after surgery. The prevalence of excessive perineal descent will be compared between groups using the Chi-square test.

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Secondary

Measure	Time frame
The presence of additional risk factors for poor surgical outcomes following ODS surgery, measured by comparing, between the two groups, the median age, sex, median duration of symptoms, prevalence of diabetes, heart disease, connective tissue disorders, neurological conditions, and the prevalence of various pelvic morphological abnormalities identified through defecographic or defeco-MRI examinations. Statistical comparisons will be performed using the Chi-square test or the Kruskal-Wallis test, depending on the characteristics of the variables considered (categorical or continuous).	—

Measure

Time frame

The presence of additional risk factors for poor surgical outcomes following ODS surgery, measured by comparing, between the two groups, the median age, sex, median duration of symptoms, prevalence of diabetes, heart disease, connective tissue disorders, neurological conditions, and the prevalence of various pelvic morphological abnormalities identified through defecographic or defeco-MRI examinations. Statistical comparisons will be performed using the Chi-square test or the Kruskal-Wallis test, depending on the characteristics of the variables considered (categorical or continuous).

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Countries

Italy, Poland

Contacts

Public ContactAntonio Brillantino

antonio.brillantino@aocardarelli.it+393290119127

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026