Croup (laryngotracheobronchitis) Respiratory Croup (laryngotracheobronchitis)
Conditions
Interventions
Patients will be randomly allocated to receiving ,additionally to the standard croup treatment, either Heliox21 (study group) or Air (control group). Comparison will be made of the primary and second
Sponsors
University Hospitals of Leicester NHS Trust (UK)
Eligibility
Inclusion criteria
Inclusion criteria: Children, aged six months to five years, presenting to the Emergency Department (ED) with moderate to severe croup (Modified Westley Croup Score of two or more).
Exclusion criteria
Exclusion criteria: 1. Children whose oxygen saturation is less than 95% 2. Children with known pre-existing lung or airway disease, congenital heart disease, or features suggesting other causes of stridor, such as peritonsillar abscess, epiglottitis or inhaled foreign body
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Westley Croup Score at 30 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Croup score at 15 minutes 2. Respiratory rate at 15, 30 minutes 3. Parents assessment of change on Visual Analog Scale 4. Number of epinephrine nebulisers given 5. Requirement for supplemental oxygen therapy 6. Admission to hospital 7. Intubation rate 8. Length of stay in ED 9. Length of stay in hospital 10. Subsequent use of health services | — |
Countries
United Kingdom
Outcome results
None listed