Colorectal cancer Cancer Malignant neoplasms of digestive organs
Conditions
Interventions
Current interventions as of 19/08/2019:
Control arm:
Treatment as Usual (TAU) comprising the patient information leaflet and study follow-up visits only. No other information relating to peri-operativ
Sponsors
Norfolk and Norwich University Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female participants = 18 years old 2. Awaiting a curative elective colorectal resection for cancer 3. American Society of Anaesthesiologists physical status I-III (ASA, 2014) 4. Able and willing to provide informed consent 5. Understand verbal and written instructions in English 6. Patients who are already participating (or have participated) in other trials may be eligible, but this must be agreed in advance by the relevant trial teams
Exclusion criteria
Exclusion criteria: 1. Contra-indications to exercise (e.g. lower limb amputation without prosthesis, orthopaedic disorder exacerbated by exercise, chronic lung disease causing desaturation with exercise or shortness of breath at rest, severe psychiatric health problems) 2. Cardiovascular contraindications (e.g. unstable angina, acute left ventricular failure, uncontrolled cardiac arrhythmias, uncontrolled hypertension, cardiac event in the previous 6 weeks, cerebral vascular disease resulting in transient ischaemic attacks) 3. Participation in other treatment trials, where this has not been agreed in advance with both trial teams
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Health-related quality of life is measured using the Study Short-Form Health Questionnaire (SF-36) at baseline and 12 months post-randomisation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Post-operative morbidity is measured 30 days post-surgery 2. Cardiopulmonary fitness 3. Grip strength 4. Length of hospital stay is recorded at discharge following operation 5. Fitness for discharge is recorded at discharge following operation 6. Re-admission rate is determined 90 days post-surgery 7. Post-operative mortality is measured 90 days post-surgery 8. Physical activity behaviour is measured 6 and 12 months 9. Psychological health status is measured 6 and 12 months | — |
Countries
England, Scotland, United Kingdom
Contacts
Public ContactBeauty Mutandari
Outcome results
None listed