Allergy and asthma Respiratory Other and unspecified effects of external causes
Conditions
Interventions
Recruitment took place 3 - 4 months before the treatment started. After randomisation patients were allocated to two groups: active and sham filters placed in the living and bedroom of families with a
Sponsors
Incen AG (Switzerland)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 6 to 18 years 2. Significant cat or dog allergen exposure greater than 500 ng/g in house dust 3. A doctor's diagnosis of asthma, sensitisation (serum Immunoglobulin E [IgE] to cat and/or dog)
Exclusion criteria
Exclusion criteria: 1. Systemic corticosteroids 2. Mite allergy above 0.7 KU/L 3. Missing consent of parents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Forced Expiratory Volume in one second (FEV1) after cold air challenge on month 0, 6 and 12. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Symptom score 2. Quality of life questionnaire 3. Cat and dog allergen exposure in bulk dust and filters 4. Eosinophil Cationic Protein (ECP) levels in serum as a marker of inflammation Secondary outcomes were measured on month 0, 6 and 12. | — |
Countries
Germany
Outcome results
None listed