Effects of exercise on the heart, blood vessels and quality of life in individuals on two antihypertensive drugs

Effects of regular physical exercise training on heart and blood vessels health indices and quality of life of individuals on two antihypertensive drugs without blood pressure control: a randomised control trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN81952488

Enrollment

120

Registered

2012-02-24

Start date

2009-09-01

Completion date

Unknown

Last updated

2017-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension Circulatory System Essential (primary) hypertension

Interventions

The participants were randomly assigned to either exercise group or control group using a computer-generated randomized number. Exercise group = aerobic dance with antihypertensive drug therapy The

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 18 years of age 2. Essential uncontrolled hypertension on 1 or 2 antihypertensive drugs 3. Resting BP from 140/90 to less than180/110mmHg

Exclusion criteria

Exclusion criteria: 1. Currently pregnant or breast-feeding individuals 2. Cardiovascular diseases such as: 2.1. Unstable angina and arrhythmia 2.2. Class IV heart failure 2.3. Uncontrolled sustained tachyarrhythmias or bradyarrhythmias 2.4. Severe and symptomatic aortic or mitral stenosis 2.5. Hypertrophic obstructive cardiomyopathy 2.6. Active or suspected myocarditis or pericarditis 2.7. Thrombophlebitis 2.8. Recent significant systemic or pulmonary embolus 3. Syncopal disorder or orthostatic hypotension of defined by greater or equal to 20 mmHg decrease in standing systolic blood pressure (SBP) as compared to sitting SBP at screening or greater or equal to10 mmHg decrease in standing diastolic blood pressure (DBP) as compared to sitting DPB at screening 4. Participants with BP not less than180/110mmHg 5. Individuals with hyperglycaemia (diabetes)

Design outcomes

Primary

Measure	Time frame
1. Systolic blood pressure 2. Diastolic blood pressure 3. Number of antihypertensive drug 4. Quality of life	—

Secondary

Measure	Time frame
1. Physical work capacity 2. Body mass index 3. Percent body fat 4. Waist circumference 5. Total cholesterol 6. Low-Density Lipoprotein (LDL) cholesterol 7. High-Density Lipoprotein (HDL) cholesterol 8. Triglyceride	—

Countries

Nigeria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026