Amnio infusion in preterm premature rupture of membranes

Amnio infusion in preterm premature rupture of membranes (AMIPROM study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN81932589

Enrollment

Registered

2004-09-30

Start date

2007-10-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth: Preterm premature rupture of membranes Pregnancy and Childbirth Preterm premature rupture of membranes

Interventions

Randomised controlled trial. Women with very early premature rupture of membranes will be randomised into (a) expectant management or (b) serial amnioinfusions.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 15 women with premature rupture of membranes in each arm

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
The study will compare the neonatal, maternal and pregnancy outcomes in pregnancies with very early PROM managed expectantly with those managed with serial amnioinfusions (replacement of fluid into the amniotic sac).	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026